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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cce19ad7f5d129f31eebaa579d3c91d449dcf3bca4567fa818fe894e1624a6f' 
  AND token = '0Y71DkCQ17gg51TQm6OZH0d4zvpsmycZLBWjSVbjrhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}