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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa247c1a4b0cb338de35e5a391c8f234e2e29b6f9cc12cc23e2a4ee57614b53' 
  AND token = 'DmJQ5yeLYMlqnr46VD7BvgmsSYvbvZ8f51UWcaOxDsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}