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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e319a039b18b42a2fa3edcca8f56d22278d588dacf1e15eff1aecafb4623fa' 
  AND token = 'KVmVMm/1wEakUD85qK+2SkK1/EzGoHjmnSFf2yGY/Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}