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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73977c14d8112fede76e59430a844ee5d1e6952554352cee62546799e47e47c4' 
  AND token = 'drRs5A85z648dL2U/Qg3IrkK/MwMfgK9/wcsiFYL5dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}