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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d994b134536a40362bf90f49b49be623ce8043a914ce10be602c37bbcd839c' 
  AND token = 'JP4Ow2SUEBBgE8uhMXsh6CLx6fIQPu80LHJ0nqTJeuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}