SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80645ea53b4867fe0d2a0f34de1b32dc3d49b39da1c20434b50705c0c641f6d' 
  AND token = 'SQ+/kvbm3oP2HETIfciggqZ3kX5qTP/ahOyO+YUdwnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}