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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353ad4f3e60429ac89224f3f6846ea410c26367af31830bdb9ed08e0a415deee' 
  AND token = 'BAHCCaGBa/wglVQnYMQbk+UOs3x66kdYtVz+jdiySEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}