SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f46ada2475b9414e995365e38b0e2b841499b07a3f4b2383890fc994cb1fb9d9' 
  AND token = 'yAGmmOSOuoWtdKeklqy3RA/xavJFo6caLczN3ZtVH8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}