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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19860b2741a6a62388d30255e243774e0846f55f2bb64c2e56e3163ccc16c935' 
  AND token = 'AEZUpxC3WiJ2XKKIDk3IlRAU6crBs2HRbixbCDwF25I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}