SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0db43c415d854c14942fa264c158952bef08519a2045676efe25f9882e2187' 
  AND token = 'mxdx6ZXO475K3TtAI3hze2Uf7qb0DO2BdnST+oI3E+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}