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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca2be083347fa2da9337f1f25cd2204991e583021c50bad89240e391e6a3898' 
  AND token = 'uS3YvHSOe1oTF1Duv+0KgW5B4M0ZLeymp36G+f7/T2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}