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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9b3edc7f436d48865a3360d1d9cdd6662c3675362322a955312d810370e4f8' 
  AND token = 'POYzTImKl0wjexXZ9rzSO+3c0K4tuNhibAIADdPAqvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}