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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d01c48dcb89bc31cc5a223e31afae70a72c56b7aa8691a9dd128ed2d9a56a1d' 
  AND token = '5M6VbFSekEZpPCRtEuFnDOfD6BnjzEKazi83D60zYl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}