SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be151f8ecfe31f648d900ffee51464d5f8d0a229426d5626c0ac40688a5b102' 
  AND token = 'o6S9OKFbs2veFMglzEd0IuSQwxNrn2oDe+jQVjAs5ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}