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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb6f81cdd094ae882b79633c9760dea9331459a9ee27195189ce45e7f68acea' 
  AND token = 'mPtx1RsK/jPzX8ZK7LIMbqq4LK/osHbbK1ZNNRMkZ2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}