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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab36a3c88d26471134c1fd6887778212a5279ef481d5c14c2f8a732909c2b75f' 
  AND token = 'wp6qC3Mt5Gs7na1fBtsDeG7DuI+ArOx+jc796gVtbh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}