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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39a4c0776a38eb3e1b5ab8001c403cf03953fb9fe943920697a3a48298c94c6' 
  AND token = 'xYpg1jZsSHt0ab2toKg71VXGPsKZMIFRIZZHHc3L5L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}