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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3ee11a150b59fe7407ce006002e661689917a5fb474d9d2468a3caf34302ce' 
  AND token = 'PGVynnbsYO9xcj1UiFzfTUzCWQ8nO34xpvlgjh9HNwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}