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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0271a0b032a19e2fa5035455f66b3c9665faec543d90244d8d5ce33f2f8f9dad' 
  AND token = 'oCRkNwfvjB4f9T+zZm6C5v/yoZmAkoW6SZrenAQafL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}