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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7e6730c9902ea7917efcbbd5552ea9c6c793c8632633ce521c00ac9f734000' 
  AND token = 'Vfi0VUtppNChD9hfv5oHCQHEjvZJc7lEqUnWDvueG1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}