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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50536dcd02af64df1d85bcffd96d3c624c1dd1afe638765c3c8b72cc7128d45b' 
  AND token = '8m6CNqutVx0y/3aADl6kDpuOlPhO0UyxaxigWarqxvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}