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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca92277c6277d353df44494636e419f049737f407b8ea114e7d55026e44a5c4' 
  AND token = 'Vr/uuiVPlPwTCgr62Iu8dRzVCZsrk0JvkLnOf2I6Z20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}