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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f59456e4ec363d4cdb0e4c981f494c7a90f1a196c574e339556e1196df33fe' 
  AND token = 'z81eDyEf+2NcKVURSmE5/Q+im+VxncCJKy+eN8VMuTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}