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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4641c807b536c459bd67f5716e0b7394e7997523b23dad2f1abcc62654bc7010' 
  AND token = 'WlEg7Lw0RtQeCJ/NX8QCv0E3sWHM9gFygHL3uDMHjsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}