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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd28f4c9d58c83ae5131e4716b7d2dbbea81d9d0db0ccc7ba3e38b4fa617bc5' 
  AND token = 'aTQAkGaFlI6QuqJ2osFmGwf4fJB+NbL59tHblgDcbzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}