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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a0203eabc1bb3c4a128923f1047b4b99cca4ba072ccfeb322777d03a3a9f91' 
  AND token = 'zvljg/WhLBd8L+GiGe9ExRM2IBjoAztda7xma2Ylss8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}