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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c122cb1cb43063c700f18973d5a6e80a72559ac301ffdd97d86c5c07064600d5' 
  AND token = 'T0EbTqZfFs6x4oKAsxMao2JhX5M1eTgL2WhL2zKr9ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}