SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03065b4bd06a8d0692f9ac4dd4477b28babab4cdb4733d24840284cd0afeacec' 
  AND token = 'tYQnwnB/nu9SxS2VTy+ScmwS7ZVTG+dCwLPxJejbt9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}