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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3177d7c9468183b7380781c414ebf4d4d7e741bd22c4c800fed2c42710f1a570' 
  AND token = '/dwcR95M61xzxM/qmNAFyeM/kIHNLfoh92lLiPC8oFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}