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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '556b454edf2876306b34022d3e802d5a77fbccd7bbda13b8a46b426f067bf181' 
  AND token = 'JMJGA1NImFBuX/EBa7FY/ZLe/8x0Xezwmtffdg1Myc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}