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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f024a0b55c9ee0218622b7fbe73e9e6ef8c17ae2e9e592b08930feb95341373' 
  AND token = 'ChlJOC0u/LPT+WkKbPNv2nnEDla3kDyyvAYxujVmpyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}