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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667cc116a8d9d9d54b1a25448a1e30385c90171d742ce9ef28a6074de9c6d41b' 
  AND token = 'RRP11FQQ1L0dhCyCT8r+9CZxenQ3wQcF5Z6DTNzvNBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}