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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ae5c0e3bf014275e63ce59a351e07e29788c92ab03b6a519ffbfade5c12779' 
  AND token = 'P8IR2vhTDJHXhwhozThGQQmC5Aia1FmrZ0O+IlKnHqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}