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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acaf1e8adf0e6378cb017be3de1365d24b90c592bb80ea4ed57ead2fa4f8a5f2' 
  AND token = 'Sv7ETSb1Y+d9dlyNg2JUmBu5Nd+bNeDVo8swrU5lzBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}