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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1452f9840eeacb0643673979d77fc139508358bce67bd773e1cdd69c40460c54' 
  AND token = 'b8VBZSOeoErs8Y/Tgb6pvxpsSRwkg5akx8Zte4UGB7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}