SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b26d1ad7f0527227a916d258a7f8b4058d971ed2de314b3b11eefa3185e5deb3' 
  AND token = 'nUU03RGx/qFypLp00K9mQ1zQI79dgHGqegkEjWQF0fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}