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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd33ca786ebc9ea9ed11363d4a7970e0f6080f05e0734d7881be954797de4a94f' 
  AND token = 'nnfmWvW7mTw4mvmw5AuBo5ByxpQswGt9JFmgDBUFtyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}