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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fdee7e2b3fdcd09f99abb0fa83183a55382d8e0062305b0e48fd8b4daccc61c' 
  AND token = '/7F9jPEux+CO3O9hh8xOvng+D4gPP3IWGuhDXpAWYd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}