SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35caef1b95bfc05bc240cab22f3866bdfe0a6e2bfcef0cfd6adc170edb259301' 
  AND token = '8DgxK6pf/i5qVvBJDZfKOjqF80bdlQqXOeBAzwf6oAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}