SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff07b32b5cdd140dc5bcf24f5a1e6506675961641f9527be891eeaac502d0635' 
  AND token = 'ZniItgATiQbh9QyJb520hlIKi/DCswu2t+FtTa56Ik0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}