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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35edd1242973457fcdbcc1c00b5987f888dec945a46b78376ffec1729d1873a9' 
  AND token = '/XLZdTnKauAQMADnX0IyFaAeM7NutVTCn2Y10w2TWEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}