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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf960fd00f13ee42b70d0e0ad587d3e651c37334a560b8dabdd61c4e812e2bc' 
  AND token = 'lxsz2LvIA9V9pxh4C2B6CdD3pdV5wI1elX0hOFf1hfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}