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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6fe4d395aac59aec38b688d1e6edcdf5f02e992fee66e28523115b9a08d6d6' 
  AND token = 'QReaZmr3GrOheHakMKQoPZIdw90sy1Q4G7KVHc15MLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}