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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1769a4c2d63fc56a1e4740c3d8b4ead0b70bffdd64bec163844da6f9203c4cdb' 
  AND token = 'oGj3MLvn9kZnKsJDTvT4ww+QQlnOYK4iBsF4doJIWeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}