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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81838b1cb79872d2ce3ba3d0c618595a36f5b0ee556d7b8f55acf552ef5feedb' 
  AND token = 'Uxu1IW0tcUk+gFd8+4S7mrgzPdTU2bWWIg3xqyReRx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}