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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43ae2c653ca56756bcc6f7d66bd4fc400457f2ebb9f027c0f7e5b225b126dfe' 
  AND token = 'HwlZIVC5n3315xfZHNBN5tPhxYqlg0eof4MbLTmnhh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}