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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d5a5c77087d42db6e8c516c9f8a77f1cd4f783c3400a763f6139bde593a9fa8' 
  AND token = 'nwDYpir7beovsy5hw9KAuEytWcg+jrw1AFN03/SmvT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}