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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8801964d7fe0ab7f6a8b70d0dd8e499b87499585ba85b9af95429ee7a5f9abd6' 
  AND token = 'HOU0ke2GPJBRbw3bH3rTW3kX/SnlPUHBmcx5dy0hSj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}