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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84c69445aa5ff661dae8a88833c9274535064f8ba31df9b2057662f4ee4f8a5d' 
  AND token = '78A90FEC/3PqFrz7ffCBRQHoYvGjd3X0jOD3/k5zGuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}