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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef909dc3e6795fc32c36a378206d321d2c55345f6bc352c07e122ebf98c5cac1' 
  AND token = '6pE4DnkMvFU6IFh9MWuOeROnmyZAcgM9Yz/swa6WJCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}